A sensing platform combining carbon dots (CDs, with blue emission) and thiomalic acid (TMA)-capped AgInS₂ quantum dots (QDs, with orange emission) was developed aiming the photoluminescence (PL) ratiometric determination of ibandronic acid (IBAN), a bisphosphonate pharmaceutical. The ternary AgInS₂ QDs were used for IBAN probing, undergoing a concentration-related PL quenching in its presence, whilst the PL of CDs remained practically unaffected due to its chemical inertness towards the antiresorptive drug, provided an intrinsic self-reference fluorophore. In addition, a visual sensing approach was also proposed, employing for the first time ternary QDs. This relied on RGB images acquired by means of a digital camera and seek the development of a rapid IBAN screening test. The developed sensing platforms were employed for IBAN determination in samples with pharmaceutical interest providing good results, in accordance to the reported IBAN levels, and obtaining recovery values between 98 and 103%.

针对伊班膦酸 (IBAN) 的光致发光 (PL) 比率测定，开发了一种结合碳点 (CDs，具有蓝色发射) 和硫代苹果酸 (TMA) 封端的 AgInS ₂量子点 (QD，具有橙色发射)的传感平台。双膦酸盐药物。三元AgInS ₂QD 用于 IBAN 探测，在其存在下经历与浓度相关的 PL 淬灭，而 CD 的 PL 由于其对抗吸收药物的化学惰性而实际上不受影响，提供了内在的自参考荧光团。此外，还提出了一种视觉传感方法，首次采用三元量子点。这依赖于通过数码相机获取的 RGB 图像，并寻求开发快速 IBAN 筛选测试。根据报告的 IBAN 水平，开发的传感平台用于测定具有药用价值的样品中的 IBAN，并获得 98% 至 103% 的回收率值，提供了良好的结果。