Eight undescribed sesquiterpenoids, including two eudesmane glycosides dobinosides A and B, five eudesmane aglycones dobinins Q-U, and one germacrane dobinin P, were isolated from the 80% ethanol extract of roots of Dobinea delavayi. Their structures were elucidated by extensive spectroscopic data (1D and 2D NMR, HR-ESI-MS) and single-crystal X-ray diffraction analysis. Dobinoside A, dobinins Q and R, as well as six reported eudesmane sesquiterpenoids, were evaluated for their in vivo antimalarial activities against Plasmodium yoelii BY265RFP in mice. A summary of preliminary structure-activity relationship of eudesmane sesquiterpenoids for in vivo antimalarial activity was described.

八个未描述的倍半萜类，其中包括两个eudesmane苷dobinosides A和B，五节eudesmane苷元dobinins QU，和一个吉马烷dobinin P，从根的80％乙醇提取物中分离九子母属缨。通过广泛的光谱数据（1D 和 2D NMR、HR-ESI-MS）和单晶 X 射线衍射分析阐明了它们的结构。Dobinoside A，dobinins Q和R，以及6个报告eudesmane倍半萜，它们的评价体内抗抗疟疾活性约氏疟原虫的小鼠BY265RFP。描述了eudesmane倍半萜类化合物在体内抗疟活性的初步构效关系的总结。