Advances in the reduction of quinolines to 1,2,3,4‐tetrahydroquinolines,Journal of Heterocyclic Chemistry

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Advances in the reduction of quinolines to 1,2,3,4‐tetrahydroquinolines
Journal of Heterocyclic Chemistry ( IF 2.0 ) Pub Date : 2021-10-30 , DOI: 10.1002/jhet.4394
Mahmoud El‐Shahat ₁

Affiliation

The pursuit of modern sustainable chemistry has stimulated the development of innovative catalytic processes that enable chemical transformations to be performed under mild and clean conditions with high efficiency. Herein, we report that the hydrogenation of heteroaromatic compounds is one of the most efficient methods for the construction of heterocyclic skeletons, and only a few promising progress has been achieved. Transition metal-catalyzed, a countless number of transition metals include have been used toward the development of homo/heterogeneous hydrogenation of quinolines via the most convenient route (Direct Hydrogenation) to obtain the corresponding tetrahydroquinoline derivatives.

中文翻译：

将喹啉还原为 1,2,3,4-四氢喹啉的研究进展

对现代可持续化学的追求刺激了创新催化工艺的发展，使化学转化能够在温和、清洁的条件下高效进行。在此，我们报道了杂芳族化合物的氢化是构建杂环骨架最有效的方法之一，并且只取得了一些有希望的进展。在过渡金属催化下，无数的过渡金属已被用于开发喹啉的均相/多相氢化，通过最方便的途径（直接氢化）获得相应的四氢喹啉衍生物。

更新日期：2021-10-30

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