当前位置: X-MOL 学术Aggregate › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Chemiluminescence: From mechanism to applications in biological imaging and therapy
Aggregate ( IF 13.9 ) Pub Date : 2021-10-28 , DOI: 10.1002/agt2.140
Zhijia Wang 1, 2 , Jiaguo Huang 2 , Jingsheng Huang 2 , Bingran Yu 1 , Kanyi Pu 2, 3 , Fu‐Jian Xu 1
Affiliation  

Chemiluminescence (CL) is an emission phenomenon induced by chemical reaction. Different from the photoluminescence, CL is free from external excitation source, which is expected to show great advantages such as higher signal-to-background ratio (SBR) in bioimaging, and deeper tissue penetration in photodynamic therapy (PDT). This review introduces the theoretical aspects of CL mechanism, such as classification, energy consideration and chemiexcited/photoexcited states. Application of CL in bioimaging is highlighted. In particular, the approaches to modulate the brightness and the wavelength of CL are summarized, which are two fundamental parameters in bioimaging. Finally, the application of CL in PDT is introduced. The potential challenges and perspectives of CL in bioimaging and therapy are also discussed.

中文翻译:

化学发光:从机制到在生物成像和治疗中的应用

化学发光(CL)是一种由化学反应引起的发光现象。与光致发光不同,CL 无需外部激发源,有望在生物成像中显示出更高的信背景比(SBR)和光动力疗法(PDT)中更深的组织穿透等巨大优势。本综述介绍了 CL 机制的理论方面,例如分类、能量考虑和化学激发/光激发态。重点介绍了 CL 在生物成像中的应用。特别是总结了调节 CL 的亮度和波长的方法,这是生物成像中的两个基本参数。最后介绍了CL在PDT中的应用。还讨论了 CL 在生物成像和治疗中的潜在挑战和前景。
更新日期:2021-10-28
down
wechat
bug