A novel series of optically active molecules based on a 4‐(2‐(benzhydryloxy)ethyl)‐1‐((R)‐2‐hydroxy‐2‐phenylethyl)‐piperidin‐3‐ol template were developed. Depending on stereochemistry, the compounds exhibit various degrees of affinity for three dopamine, serotonin, and norepinephrine transporters. These molecules have the potential for treating several neurological disorders such as drug abuse, depression, and attention deficit hyperactivity disorder.

中文翻译：

---

(3R,4R)-4-(2-(Benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol 的合成和生物学表征及其对单胺活性的立体异构体运输者

开发了一系列基于 4-(2-(二苯甲基氧基)乙基)-1-(( R )-2-羟基-2-苯乙基)-哌啶-3-醇模板的新型光学活性分子。根据立体化学的不同，这些化合物对三种多巴胺、血清素和去甲肾上腺素转运蛋白表现出不同程度的亲和力。这些分子具有治疗多种神经系统疾病的潜力，例如药物滥用、抑郁症和注意力缺陷多动障碍。