Terrein is a small-molecule polyketide compound with a simple structure mainly isolated from fungi. Since its discovery in 1935, many scholars have conducted a series of research on its structure identification, isolation source, production increase, synthesis and biological activity. Studies have shown that terrein has a variety of biological activities, not only can inhibit melanin production and epidermal hyperplasia, but also has anti-cancer, anti-inflammatory, anti-angiopoietic secretion, antibacterial, insecticidal activities, and so on. It has potential application prospects in beauty, medicine, agriculture and other fields. This article reviews the process of structural identification of terrein since 1935, and summarizes the latest advances in its isolation, source, production increase, synthesis, and biological activity evaluation, with a view to providing a reference and helping for the in-depth research of terrein.

中文翻译：

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Terrein 的分离、合成和生物学评价的最新进展

Terrein是一种结构简单的小分子聚酮化合物，主要从真菌中分离得到。自1935年被发现以来，许多学者对其结构鉴定、分离来源、增产、合成及生物活性等进行了一系列研究。研究表明，土霉素具有多种生物活性，不仅能抑制黑色素生成和表皮增生，还具有抗癌、抗炎、抗血管生成、抗菌、杀虫等活性。在美容、医药、农业等领域具有潜在的应用前景。本文回顾了1935年以来土霉素的结构鉴定过程，总结了其分离、来源、增产、合成、生物活性评价等方面的最新进展，