Therapeutic plasma exchange for peripheral neuropathy associated with trisulfated heparan disaccharide IgM antibodies: A case series of 17 patients,Journal of Clinical Apheresis

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Therapeutic plasma exchange for peripheral neuropathy associated with trisulfated heparan disaccharide IgM antibodies: A case series of 17 patients
Journal of Clinical Apheresis ( IF 1.4 ) Pub Date : 2021-10-26 , DOI: 10.1002/jca.21944
Gregory M Olsen ₁ , Christopher A Tormey ₁ , Bertrand Tseng ₂ , Jeanne E Hendrickson _{1,

3} , Nataliya Sostin ₁

Affiliation

Small fiber neuropathy (SFN) can be associated with autoantibodies, including those of IgM class with specificity for the trisulfated heparan disaccharide (TS-HDS) antigen. We hypothesized that, as an IgM autoantibody-mediated disorder, TS-HDS-associated SFN symptoms may be reduced with therapeutic plasma exchange (TPE).

中文翻译：

与三硫酸化乙酰肝素二糖 IgM 抗体相关的周围神经病变的治疗性血浆置换：17 名患者的病例系列

小纤维神经病变 (SFN) 可能与自身抗体相关，包括对三硫酸化乙酰肝素二糖 (TS-HDS) 抗原具有特异性的 IgM 类抗体。我们假设，作为一种 IgM 自身抗体介导的疾病，TS-HDS 相关的 SFN 症状可以通过治疗性血浆置换 (TPE) 来减轻。

更新日期：2021-10-26

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