Background

Zeaxanthin is a carotenoid pigment found in several fruits and vegetables. Belonging to the xanthophyll family, it is widely present in human and some animals skin and eyes, performing important physiological functions due to its antioxidant and anti-inflammatory effects. Several studies have explored its health benefits against important disorders such as neurological diseases, allergies, and cancer.

Scope and approach

The aim of this study we to explore the sources, health benefits, and biological properties of zeaxanthin and analyzes its drug interaction with β-carotene.

Key findings and conclusion

Severela vegetable sources in particularly fruits parts contains zeaxanthin. Biological investigations showed that zeaxanthin has been found to exhibit a protective effect against excessive light and oxidative stress side effects, preventing the development of several neurological, skin, and eye disorders. It exhibits also antioxidant, antiparasitic, anthelmintic activity, and antiosteoporosis effects. Zeaxanthin can also play a role in the inflammatory response, contributing to the treatment or prevention of diseases like allergies and AIDS. Additionally, zeaxanthin can exhibit anticancer, anti-osteoporotic, and ophthalmologic effects. These different properties are mediated by diffetent cellular and molecular mechanisms exhibited by zeaxanthin such as its activation and/or blocker of cell receptors, its actions on signaling pathways, and also its effects on gene expression. Moreover, the safety as a dietary supplement has also been confirmed and its interaction with other carotenoids, such as β-carotene, has been studied and validated in pharmacokinetic investigations. However, further investigations are needed to explore the full potential of zeaxanthin and to elucidate more its molecular pharmacodynamic actions behind its effects on human health, and to investigate also its clinical applications.

中文翻译：

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玉米黄质的来源、健康益处和生物学特性

背景

玉米黄质是一种存在于多种水果和蔬菜中的类胡萝卜素色素。属于叶黄素家族，广泛存在于人类和一些动物的皮肤和眼睛中，由于其抗氧化和抗炎作用而发挥重要的生理功能。几项研究探索了它对神经系统疾病、过敏和癌症等重要疾病的健康益处。

范围和方法

本研究的目的是探索玉米黄质的来源、健康益处和生物学特性，并分析其与 β-胡萝卜素的药物相互作用。

主要发现和结论

Severela 蔬菜来源，特别是水果部分含有玉米黄质。生物学研究表明，玉米黄质已被发现对过度光照和氧化应激副作用具有保护作用，可防止多种神经、皮肤和眼部疾病的发展。它还具有抗氧化、抗寄生虫、驱虫活性和抗骨质疏松作用。玉米黄质还可以在炎症反应中发挥作用，有助于治疗或预防过敏和艾滋病等疾病。此外，玉米黄质还具有抗癌、抗骨质疏松和眼科​​作用。这些不同的特性是由玉米黄质表现出的不同细胞和分子机制介导的，例如其激活和/或细胞受体阻滞剂、其对信号通路的作用、以及它对基因表达的影响。此外，作为膳食补充剂的安全性也已得到证实，其与其他类胡萝卜素（如 β-胡萝卜素）的相互作用已在药代动力学研究中得到研究和验证。然而，还需要进一步的研究来探索玉米黄质的全部潜力并阐明其对人类健康影响背后的分子药效学作用，并研究其临床应用。