当前位置：
X-MOL 学术
›
J. Org. Chem.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Titanium(IV)-Mediated Ring-Opening/Dehydroxylative Cross-Coupling of Diaryl-Substituted Methanols with Cyclopropanol Derivatives
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2021-10-10 , DOI: 10.1021/acs.joc.1c01790 Si-Xuan Zhang 1 , Yan Ding 1 , Jun-Jie Wang 1 , Chuanji Shen 2 , Xiaocong Zhou 2 , Xue-Qiang Chu 1 , Mengtao Ma 3 , Zhi-Liang Shen 1
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2021-10-10 , DOI: 10.1021/acs.joc.1c01790 Si-Xuan Zhang 1 , Yan Ding 1 , Jun-Jie Wang 1 , Chuanji Shen 2 , Xiaocong Zhou 2 , Xue-Qiang Chu 1 , Mengtao Ma 3 , Zhi-Liang Shen 1
Affiliation
|
A titanium(IV)-mediated ring-opening/dehydroxylative cross-coupling of diaryl-substituted methanols with a cyclopropanol derivative was developed. The reactions proceeded efficiently to provide synthetically useful γ,γ-diaryl esters in moderate to good yields, which could be applied to the functionalization of complex molecules derived from bioactive fenofibrate and isoxepac and the synthesis of a precursor of Zoloft.
中文翻译：
钛 (IV) 介导的二芳基取代甲醇与环丙醇衍生物的开环/脱羟基交叉偶联
开发了一种钛 (IV) 介导的二芳基取代的甲醇与环丙醇衍生物的开环/脱羟基交叉偶联。该反应有效地进行，以中等至良好的收率提供合成有用的 γ,γ-二芳基酯，可应用于衍生自生物活性非诺贝特和异恶唑的复杂分子的官能化以及唑洛夫特前体的合成。
更新日期：2021-11-05
中文翻译：
钛 (IV) 介导的二芳基取代甲醇与环丙醇衍生物的开环/脱羟基交叉偶联
开发了一种钛 (IV) 介导的二芳基取代的甲醇与环丙醇衍生物的开环/脱羟基交叉偶联。该反应有效地进行，以中等至良好的收率提供合成有用的 γ,γ-二芳基酯，可应用于衍生自生物活性非诺贝特和异恶唑的复杂分子的官能化以及唑洛夫特前体的合成。
京公网安备 11010802027423号