The potential of cellulolytic enzymes has been widely studied and explored for bioconversion processes and plays a key role in various industrial applications. Cellulase, a key enzyme for cellulose-rich waste feedstock-based biorefinery, has increasing demand in various industries, e.g., paper and pulp, juice clarification, etc. Also, there has been constant progress in developing new strategies to enhance its production, such as the application of waste feedstock as the substrate for the production of individual or enzyme cocktails, process parameters control, and genetic manipulations for enzyme production with enhanced yield, efficiency, and specificity. Further, an insight into immobilization techniques has also been presented for improved reusability of cellulase, a critical factor that controls the cost of the enzyme at an industrial scale. In addition, the review also gives an insight into the status of the significant application of cellulase in the industrial sector, with its techno-economic analysis for future applications. The present review gives a complete overview of current perspectives on the production of microbial cellulases as a promising tool to develop a sustainable and greener concept for industrial applications.

纤维素分解酶的潜力已在生物转化过程中得到广泛研究和探索，并在各种工业应用中发挥着关键作用。纤维素酶是富含纤维素的废原料生物精炼厂的关键酶，在造纸和纸浆、果汁澄清等各个行业的需求不断增加。此外，在开发新策略以提高其产量方面也不断取得进展，例如作为应用废物原料作为生产个体或酶混合物的底物、工艺参数控制和遗传操作来提高酶生产的产量、效率和特异性。此外，还提出了对固定化技术的深入了解，以提高纤维素酶的可重复使用性，这是在工业规模上控制酶成本的关键因素。此外，该综述还深入了解了纤维素酶在工业领域的重要应用状况，并对未来应用进行了技术经济分析。本综述全面概述了微生物纤维素酶生产的当前观点，作为开发工业应用可持续和绿色概念的有前途的工具。