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Chloramine-T in Organic Synthesis and Analysis of Organic Functional Groups: A Review
Australian Journal of Chemistry ( IF 1.0 ) Pub Date : 2021-09-30 , DOI: 10.1071/ch21089
P. T. Sowmya , K. M. Lokanatha Rai , Anitha Sudhir , Sumana Y. Kotian

The diverse nature of Chloramine-T, the sodium salt of N-chloro-p-toluenesulfonamide, abbreviated as CAT, acts as a source of halonium cation and nitrogen anion, and acts as both base and nucleophile. It reacts with broad range of functional groups and brings divergent molecular transformations to synthetic chemistry. CAT has also gained much recognition as a mild oxidant for several organic moieties and has been used as a versatile reagent for the estimation of various functional groups in analytical chemistry. This review relays the synthetic and analytic utility of CAT from different literature sources. As aspects of the synthetic utility of CAT have not previously been reviewed, this article gives a comprehensive profile of the CAT reagent for further research development.



中文翻译:

有机合成中的氯胺-T 和有机官能团的分析:综述

Chloramine-T 的多样性,N-氯-对-甲苯磺酰胺的钠盐,缩写为CAT,作为卤阳离子和氮阴离子的来源,并作为碱和亲核试剂。它与广泛的官能团发生反应,并为合成化学带来不同的分子转化。CAT 也被广泛认为是几种有机部分的温和氧化剂,并已被用作分析化学中用于估计各种官能团的通用试剂。这篇综述从不同的文献来源传达了 CAT 的综合和分析效用。由于之前尚未审查 CAT 合成效用的各个方面,本文提供了 CAT 试剂的全面概况,以供进一步研究开发。

更新日期:2021-10-02
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