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Analysis of the Indanomycin Biosynthetic Gene Cluster from Streptomyces antibioticus NRRL 8167
ChemBioChem ( IF 2.6 ) Pub Date : 2009-03-19 , DOI: 10.1002/cbic.200800822
Chaoxuan Li , Kathryn E. Roege , Wendy L. Kelly

More than meets the I: The biosynthetic gene cluster for indanomycin was identified from Streptomyces antibioticus NRRL 8167. The framework of the indanomycins includes a tetrahydropyran and a central indane ring system. The final module of the indanomycin polyketide synthase possesses an unusual terminal module lacking an integrated thioesterase.
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中文翻译:

抗生素链霉菌NRRL 8167的Indanomycin生物合成基因簇的分析

远远超过了I:从抗生素链霉菌NRRL 8167中鉴定了茚达菌素的生物合成基因簇。茚达菌素的框架包括四氢吡喃和中央茚满环系统。茚达那霉素聚酮化合物合酶的最终模块具有不常见的末端模块,缺少整合的硫酯酶。
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更新日期:2009-03-19
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