Bifunctional Smart Hydrogel Dressing with Strain Sensitivity and NIR-Responsive Performance,ACS Applied Materials & Interfaces

当前位置： X-MOL 学术 › ACS Appl. Mater. Interfaces › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Bifunctional Smart Hydrogel Dressing with Strain Sensitivity and NIR-Responsive Performance
ACS Applied Materials & Interfaces ( IF 8.3 ) Pub Date : 2021-09-24 , DOI: 10.1021/acsami.1c15312
Fan Hao ₁ , Liangyu Wang ₁ , Binling Chen ₁ , Lin Qiu ₂ , Jun Nie ₁ , Guiping Ma ₁

Affiliation

Smart response hydrogel has a broad application prospect in human health real-time monitoring due to its responses to a variety of stimuli. In this study, we developed a novel smart hydrogel dressing based on conductive MXene nanosheets and a temperature-sensitive PNIPAm polymer. γ-Methacryloxypropyltrimethoxysilane (KH570) was selected to functionalize the surface of MXene further to improve the interface compatibility between MXene and PNIPAm. Our prepared K-M/PNIPAm hydrogel was found to have a strain-sensitive property, as well as a respond to NIR phase change and volume change. When applied as a strain flexible sensor, this K-M/PNIPAm hydrogel exhibited a high strain sensitivity with a gauge factor (GF) of 4.491, a broad working strain range of ≈250%, a fast response of ∼160 ms, and good cycle stability (i.e., 3000 s at 20% strain). Besides, this K-M/PNIPAm hydrogel can be used as an efficient NIR light-controlled drug release carrier to achieve on-demand drug release. This work paved the way for the application of smart response hydrogel in human health real-time monitoring and NIR-controlled drug release functions.

中文翻译：

具有应变敏感性和近红外响应性能的双功能智能水凝胶敷料

智能响应水凝胶由于其对多种刺激的反应，在人体健康实时监测方面具有广阔的应用前景。在这项研究中，我们开发了一种基于导电 MXene 纳米片和温敏 PNIPAm 聚合物的新型智能水凝胶敷料。选择γ-甲基丙烯酰氧基丙基三甲氧基硅烷(KH570)对MXene表面进行功能化，进一步提高MXene与PNIPAm之间的界面相容性。我们制备的 KM/PNIPAm 水凝胶被发现具有应变敏感特性，以及对近红外相变和体积变化的响应。当用作应变柔性传感器时，这种 KM/PNIPAm 水凝胶表现出高应变灵敏度，应变系数 (GF) 为 4.491、宽工作应变范围 ≈250%、快速响应 ∼160 ms 和良好的循环稳定性（即 20% 应变下 3000 秒）。此外，这种KM/PNIPAm水凝胶可以作为高效的近红外光控药物释放载体，实现按需药物释放。这项工作为智能响应水凝胶在人体健康实时监测和近红外控制药物释放功能中的应用铺平了道路。

更新日期：2021-10-06

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南