Rare electrochemiluminescence (ECL) sensors have been developed based on the direct regulation of ionic current because it is difficult to establish a relationship between ionic current and ECL reporting. Ionic current can be adjusted by the effective radius and charge density of a functionalized microchannel and is frequently adopted to develop electrical sensors. Here, we show a novel ECL sensing platform that combines the microchannel-based electrical sensing technology with an ECL reporting system for the first time. The target regulated the effective radius and charge density of a microchannel which in turn adjusted the ionic transport in it and finally caused the change of ECL reporting of a tris(1,10-phenanthroline)ruthenium(II)/tripropylamine system. The developed system has already been applied to detect aflatoxin B1 for demonstration. This configuration separated the target sensing and reporting reactions to achieve direct regulation of ECL reporting by ionic current and expanded the application of the ECL detection technology to microanalysis.

中文翻译：

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通过调节微通道中的电荷密度设计电化学发光检测系统

由于很难建立离子电流和 ECL 报告之间的关系，因此基于离子电流的直接调节开发了罕见的电化学发光 (ECL) 传感器。离子电流可以通过功能化微通道的有效半径和电荷密度进行调节，并且经常用于开发电传感器。在这里，我们展示了一种新颖的 ECL 传感平台，首次将基于微通道的电传感技术与 ECL 报告系统相结合。该靶标调节微通道的有效半径和电荷密度，进而调节微通道中的离子输运，最终引起三(1,10-菲咯啉)钌( II )/三丙胺体系ECL报告的变化。所开发的系统已应用于黄曲霉毒素B1的检测并进行示范。这种配置将目标传感和报告反应分开，实现离子电流对ECL报告的直接调控，并将ECL检测技术的应用扩展到微量分析。