Development of Red-Shifted and Fluorogenic Nucleoside and Oligonucleotide Diarylethene Photoswitches,Chemistry - A European Journal

当前位置： X-MOL 学术 › Chem. Eur. J. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Development of Red-Shifted and Fluorogenic Nucleoside and Oligonucleotide Diarylethene Photoswitches
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2021-09-14 , DOI: 10.1002/chem.202103133
Theresa Kolmar ₁ , Antonia Becker ₁ , Ronja A Pfretzschner ₁ , Alina Lelke ₁ , Andres Jäschke ₁

Affiliation

The core structure of nucleoside based diarylethenes was modified, with the aim of bathochromically shifting the absorption wavelength in the visible range (λ_max,vis) and to introduce photomodulatable fluorescence. Extending the π-system of the bridging unit resulted in a desired red shift of λ_max,vis and fluorogenicity could be obtained by the introduction of a fluorescent adenosine analogue.

中文翻译：

红移和荧光核苷和寡核苷酸二芳基乙烯光开关的开发

对基于核苷的二芳基乙烯的核心结构进行了修改，目的是使吸收波长在可见光范围 (λ _max,vis ) 发生红移，并引入可光调制的荧光。扩展桥接单元的 π 系统导致所需的 λ _max,vis的红移，并且可以通过引入荧光腺苷类似物来获得荧光性。

更新日期：2021-09-14

点击分享查看原文

点击收藏

公开下载

阅读更多本刊新发论文