A simple, highly efficient method for synthesis of 1,3-dihydrofuro[3,4-b]quinoline is described by the reaction of o-arylalkynyl quinoline aldehydes with Na₂S·9H₂O via domino reduction approach. The method is simple and proceeds under mild condition under an air atmosphere to give 1,3-dihydrofuro[3,4-b]quinoline in good to excellent yields. The beauty of the reaction is cyclization as well as reduction has been taken place in the same reaction pot. Also the conversion of aldehyde into primary alcohol has been discussed under the same reaction condition.

中文翻译：

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Na2S·9H2O介导的多米诺还原法合成1,3-二氢呋喃[3,4-b]喹啉衍生物

邻芳炔基喹啉醛与Na ₂ S·9H ₂ O通过多米诺还原法反应，描述了一种简单、高效的合成1,3-二氢呋喃[3,4- b ]喹啉的方法。该方法简单，在温和条件下，在空气气氛下进行，以良好至极好的收率得到1,3-二氢呋喃[3,4- b ]喹啉。该反应的美妙之处在于在同一个反应釜中进行了环化和还原。在相同的反应条件下也讨论了醛向伯醇的转化。