Apiaceae is a family encompassing medicinal and aromatic plants. They produce essential oils (EOs) inside oil canals, known as ducts and vittae, which occur in their vegetative and reproductive organs. Given the high EO yields and the availability of raw material from cultivations widespread all over the world, Apiaceae are exploitable for different industrial applications. An interesting perspective is their utilization in the fabrication of botanical insecticides effective against insect vectors of public importance such as mosquitoes, aiming to be eco-friendly alternatives to synthetic insecticides. On this basis, in the current review, we collected scientific evidence supporting the use of Apiaceae EOs and their major constituents as active ingredients in insecticidal formulations against larvae and adults of several mosquitoes that are important pathogen vectors (e.g., Anopheles, Aedes and Culex species). For this purpose, we analysed the published data on their larvicidal, ovicidal, oviposition deterrent, pupicidal, adulticidal, and repellent effects, using efficacy thresholds as in the case of larvicidal activity (LC₅₀ (lethal concentration killing 50 % of the exposed population) < 50 ppm). Toxicity to non-target organisms, including vertebrates, has also been reviewed. The major EO constituents have been highlighted, each with its spectrum of mosquitocidal activity, providing insights on their multiple modes of action. The urgent need to develop highly stable micro/nano-formulations for real-world use has been outlined. Current weaknesses and strengths in the steps toward the development of botanical insecticides have been analysed to increase awareness of the future challenges necessary to open the doors to the industrial utilization of Apiaceae EOs by agrochemical companies.

伞形科是一个包括药用和芳香植物的科。它们在油管内产生精油 (EO)，称为导管和油管，它们发生在它们的营养和生殖器官中。鉴于高 EO 产量和来自世界各地广泛种植的原材料的可用性，伞形科可用于不同的工业应用。一个有趣的观点是它们在制造植物杀虫剂中的应用，该杀虫剂可有效对抗蚊子等具有公共重要性的昆虫载体，旨在成为合成杀虫剂的环保替代品。在此基础上，在本次审查中，蚊、伊蚊和库蚊物种）。为此，我们分析了已发表的关于它们的杀幼虫、杀卵、排卵、杀蛹、杀成虫和驱虫作用的数据，使用功效阈值与杀幼虫活性 (LC ₅₀（致死浓度可杀死 5​​0% 的暴露人群）< 50 ppm）。还审查了对非目标生物（包括脊椎动物）的毒性。重点介绍了主要的 EO 成分，每种成分都有其杀蚊活性的范围，提供了对其多种作用模式的见解。已经概述了开发用于现实世界的高度稳定的微/纳米制剂的迫切需要。已经分析了植物杀虫剂开发步骤中当前的弱点和优势，以提高对未来挑战的认识，为农化公司打开伞形科 EO 的工业利用之门。