当前位置:
X-MOL 学术
›
Org. Lett.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Carbamoylation of Azomethine Imines via Visible-Light Photoredox Catalysis
Organic Letters ( IF 4.9 ) Pub Date : 2021-08-24 , DOI: 10.1021/acs.orglett.1c02353
Bianca T Matsuo 1 , Pedro H R Oliveira 1 , José Tiago M Correia 1 , Márcio W Paixão 1
Organic Letters ( IF 4.9 ) Pub Date : 2021-08-24 , DOI: 10.1021/acs.orglett.1c02353
Bianca T Matsuo 1 , Pedro H R Oliveira 1 , José Tiago M Correia 1 , Márcio W Paixão 1
Affiliation
![]() |
A versatile and robust photocatalytic methodology to install the amide functional group into azomethine imine ions is described. This protocol is distinguished by its broad scope and mild reaction conditions, which are well suited for the preparation of structurally complex compounds in the form of amino acids, peptides, and small drug-like molecules. Moreover, the generated pyrazolidinone core could be easily converted into β-alanine analogues.
中文翻译:
通过可见光光氧化还原催化对偶氮甲碱亚胺进行氨基甲酰化
描述了一种将酰胺官能团安装到偶氮甲碱亚胺离子中的通用且稳健的光催化方法。该协议以其广泛的范围和温和的反应条件而著称,非常适合以氨基酸、肽和类药物小分子的形式制备结构复杂的化合物。此外,生成的吡唑烷酮核心可以很容易地转化为 β-丙氨酸类似物。
更新日期:2021-09-03
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
通过可见光光氧化还原催化对偶氮甲碱亚胺进行氨基甲酰化
描述了一种将酰胺官能团安装到偶氮甲碱亚胺离子中的通用且稳健的光催化方法。该协议以其广泛的范围和温和的反应条件而著称,非常适合以氨基酸、肽和类药物小分子的形式制备结构复杂的化合物。此外,生成的吡唑烷酮核心可以很容易地转化为 β-丙氨酸类似物。