子宫肌瘤切除术、UAE 和 MRgFUS 治疗子宫肌瘤的比较：荟萃分析。,International Journal of Hyperthermia

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子宫肌瘤切除术、UAE 和 MRgFUS 治疗子宫肌瘤的比较：荟萃分析。
International Journal of Hyperthermia ( IF 3.0 ) Pub Date : 2021-09-01 , DOI: 10.1080/02656736.2021.1933216
Fan Xu _{1,

2} , Lihong Deng ₁ , Lijun Zhang ₂ , Huiquan Hu ₁ , Qiuling Shi _{2,

3}

Affiliation

目的比较不同随访时间子宫肌瘤（UFs）子宫肌瘤切除术、子宫动脉栓塞术（UAE）和磁共振引导聚焦超声手术（MRgFUS）的再干预率。方法两名研究者在 PubMed 中检索 2000 年 1 月 1 日至 2020 年 12 月 31 日以英文发表的临床研究，独立审查论文以选择合格的研究，提取相关信息并评估偏倚风险。同时，对 31 项研究共 42103 名患者进行了荟萃分析，以比较子宫肌瘤切除术、UAE 和 MRgFUS 的再干预率。结果在 42103 名患者的荟萃分析中，肌瘤切除术、UAE 和 MRgFUS 对 UFs 的 12 个月再干预率分别为 0.06（95%CI，0.01-0.11）、0.07（95%CI，0.06-0.09）和0.12 (95% CI, 0.04-0.20)。24 个月的再干预率分别为 0.10（95%CI，0.04-0.16）、0.08（95%CI，0.01-0.17）和 0.14（95%CI，0.07-0.21）。36 个月的再干预率分别为 0.09（95%CI，0.05-0.13）、0.14（95%CI，0.05-0.23）和 0.22（95%CI，0.11-0.32）。此外，60 个月的再干预率分别为 0.19（95%CI，0.15-0.24）、0.21（95%CI，0.17-0.25）和 0.49（95%CI，0.21-0.77）。结论子宫肌瘤切除术在3种方案中短时、长时再干预率最低，MRgFUS最高。MRgFUS 率在治疗后第 60 个月迅速增加。32) 分别。此外，60 个月的再干预率分别为 0.19（95%CI，0.15-0.24）、0.21（95%CI，0.17-0.25）和 0.49（95%CI，0.21-0.77）。结论子宫肌瘤切除术在3种方案中短时、长时再干预率最低，MRgFUS最高。MRgFUS 率在治疗后第 60 个月迅速增加。32) 分别。此外，60 个月的再干预率分别为 0.19（95%CI，0.15-0.24）、0.21（95%CI，0.17-0.25）和 0.49（95%CI，0.21-0.77）。结论子宫肌瘤切除术在3种方案中短时、长时再干预率最低，MRgFUS最高。MRgFUS 率在治疗后第 60 个月迅速增加。

"点击查看英文标题和摘要"

The comparison of myomectomy, UAE and MRgFUS in the treatment of uterine fibroids: a meta analysis.

OBJECTIVE To compare the re-intervention rates of myomectomy, uterine artery embolization (UAE) and magnetic resonance-guided focused ultrasound surgery (MRgFUS) for uterine fibroids (UFs) in different follow-up time. METHODS Two investigators searched PubMed for clinical studies published in English from 1 Jan 2000 to 31 Dec 2020, and independently examined the paper to select qualified studies, extracted relevant information and assessed the risk of bias. Meanwhile, a meta-analysis of 31 studies containing totally 42103 patients was conducted to compare the re-intervention rate of myomectomy, UAE and MRgFUS. RESULTS In the meta-analysis of 42103 patients, the 12-month re-intervention rates of myomectomy, UAE and MRgFUS for UFs were 0.06 (95%CI, 0.01-0.11), 0.07 (95%CI, 0.06-0.09), and 0.12 (95%CI, 0.04-0.20) respectively. The 24-month re-intervention rates were 0.10 (95%CI, 0.04-0.16), 0.08 (95%CI, 0.01-0.17), and 0.14 (95%CI, 0.07-0.21) respectively. The 36-month re-intervention rates were 0.09 (95%CI, 0.05-0.13), 0.14 (95%CI, 0.05-0.23), and 0.22 (95%CI, 0.11-0.32) respectively. Additionally, the 60-month re-intervention rates were 0.19 (95%CI, 0.15-0.24), 0.21 (95%CI, 0.17-0.25), and 0.49 (95%CI, 0.21-0.77) respectively. CONCLUSIONS The myomectomy has the lowest re-intervention rate of the three regimens in short time and long time while the MRgFUS has the highest. The rate of MRgFUS increased rapidly in the 60th month after the treatment.

更新日期：2021-08-24

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