Investigation of the Impurities in Erythritol Tetranitrate (ETN) Using UHPLC-QTOF,Propellants, Explosives, Pyrotechnics

当前位置： X-MOL 学术 › Propellants Explos. Pyrotech. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Investigation of the Impurities in Erythritol Tetranitrate (ETN) Using UHPLC-QTOF
Propellants, Explosives, Pyrotechnics ( IF 1.7 ) Pub Date : 2021-08-19 , DOI: 10.1002/prep.202100193
Chris E. Freye ₁ , Thuy‐Ai D. Nguyen ₁ , Bryce C. Tappan ₁

Affiliation

In order to further gain a comprehensive chemical understanding of erythritol tetranitrate (ETN), the synthesis impurities of ETN were investigated using ultrahigh performance liquid chromatography with tandem high resolution mass spectrometry (UHPLC-MS/MS). A total of 12 impurities were identified relating to the synthesis of ETN. We have synthesized pure analytical standards of erythritol-1,4-dinitrate (1,4-EDiN) and erythritol-1,2,4-trinitrate (1,2,4-ETriN). These isomerically pure standards have allowed for confirmation of the identity of some of the discovered impurities. Additionally, partially nitrated with sulfate substituted erythritol was identified which is theorized to have formed from the incomplete displacement of the formed sulfate group on the alcohol position during nitration.

中文翻译：

使用 UHPLC-QTOF 研究赤藓糖醇四硝酸酯 (ETN) 中的杂质

为了进一步全面了解四硝酸赤藓糖醇 (ETN)，使用超高效液相色谱-串联高分辨质谱 (UHPLC-MS/MS) 对 ETN 的合成杂质进行了研究。共鉴定出 12 种与 ETN 合成有关的杂质。我们合成了赤藓糖醇-1,4-二硝酸盐 (1,4-EDiN) 和赤藓糖醇-1,2,4-三硝酸盐 (1,2,4-ETriN) 的纯分析标准品。这些异构纯的标准品可以确认一些发现的杂质的身份。此外，还鉴定出被硫酸盐取代的赤藓糖醇部分硝化，理论上认为这是由硝化过程中醇位置上形成的硫酸盐基团的不完全置换而形成的。

更新日期：2021-10-07

点击分享查看原文

点击收藏

阅读更多本刊新发论文