Functional Hydrogels as Wound Dressing to Enhance Wound Healing,ACS Nano

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Functional Hydrogels as Wound Dressing to Enhance Wound Healing
ACS Nano ( IF 15.8 ) Pub Date : 2021-08-10 , DOI: 10.1021/acsnano.1c04206
Yongping Liang ₁ , Jiahui He ₁ , Baolin Guo _{1,

2}

Affiliation

Hydrogels, due to their excellent biochemical and mechnical property, have shown attractive advantages in the field of wound dressings. However, a comprehensive review of the functional hydrogel as a wound dressing is still lacking. This work first summarizes the skin wound healing process and relates evaluation parameters and then reviews the advanced functions of hydrogel dressings such as antimicrobial property, adhesion and hemostasis, anti-inflammatory and anti-oxidation, substance delivery, self-healing, stimulus response, conductivity, and the recently emerged wound monitoring feature, and the strategies adopted to achieve these functions are all classified and discussed. Furthermore, applications of hydrogel wound dressing for the treatment of different types of wounds such as incisional wound and the excisional wound are summarized. Chronic wounds are also mentioned, and the focus of attention on infected wounds, burn wounds, and diabetic wounds is discussed. Finally, the future directions of hydrogel wound dressings for wound healing are further proposed.

中文翻译：

功能性水凝胶作为伤口敷料以促进伤口愈合

水凝胶由于其优异的生化和机械性能，在伤口敷料领域显示出极具吸引力的优势。然而，仍然缺乏对功能性水凝胶作为伤口敷料的全面综述。本文首先总结了皮肤伤口愈合过程并关联评价参数，然后综述了水凝胶敷料的抗菌性能、粘附止血、抗炎抗氧化、物质输送、自我修复、刺激反应、电导率等先进功能。，以及最近出现的伤口监测功能，以及实现这些功能所采用的策略，都进行了分类和讨论。此外，还总结了水凝胶伤口敷料在治疗切开伤、切除伤等不同类型伤口中的应用。还提到了慢性伤口，并讨论了感染伤口、烧伤伤口和糖尿病伤口的关注重点。最后，进一步提出了用于伤口愈合的水凝胶伤口敷料的未来发展方向。

更新日期：2021-08-24

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