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A CONVENIENT METHOD FOR THE DIRECT PREPARATION OF KETONES FROM 2-(6-(2-METHOXYETHYL)PYRIDYL)CARBOXYLATES AND ALKYL IODIDES BY USE OF ZINC DUST AND A CATALYTIC AMOUNT OF NICKEL DICHLORIDE
Chemistry Letters ( IF 1.4 ) Pub Date : 1981-04-05 , DOI: 10.1246/cl.1981.531
Makoto Onaka 1 , Yoshio Matsuoka 1 , Teruaki Mukaiyama 1
Affiliation  

Treatment of 2-(6-(2-methoxyethyl)pyridyl) carboxylates with alkyl iodides in the presence of zinc dust and a catalytic amount of NiCl2 in DMF at 50 °C affords unsymmetrical ketones in good yields by a one-pot procedure.

中文翻译:

通过使用锌粉和二氯化镍的催化量直接从 2-(6-(2-甲氧基乙基)吡啶基)羧酸盐和烷基碘制备酮的简便方法

在锌粉和催化量的 NiCl2 的 DMF 存在下,在 50 °C 下用烷基碘处理 2-(6-(2-甲氧基乙基)吡啶基)羧酸酯,通过一锅法以良好的收率提供不对称酮。
更新日期:1981-04-05
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