High-entropy ceramics (HECs) are novel materials with unexpected chemistry. However, HEC-based catalysis or chemistry has rarely been studied before. Herein, porous high-entropy MgAl₂O₄ (HE-MgAl₂O₄) (up to denary metals: Mg, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, and Zn) was prepared (S_BET = 139 m²/g). The synthetic chemistry, the tolerance law of different metals, and the thermodynamic rule for crystallization have been well studied. The comparison of binary-, ternary-, quaternary-, quinary-, and denary-MgAl₂O₄ highlighted the key role of entropy, which forces cations with intrinsic different radii to occupy similar sites of spinel. Interestingly, high entropy naturally endows the HE-MgAl₂O₄ catalyst with exceptional stability even when operated at high-temperature moisture (350°C) for 24 h. Then, ab initio molecular dynamics studies proved that the thermal stability of HE-MgAl₂O₄ originated from the entropy stabilization effect and kinetically stabilized structure. Moreover, CH₄ oxidation with 10 vol % steam in feeding gas was performed, and the pristine activity was preserved by the HE-MgAl₂O₄ catalyst over continuous operation (600°C, 100 h).

高熵陶瓷 (HEC) 是一种具有意想不到的化学性质的新型材料。然而，之前很少研究基于 HEC 的催化或化学。在此，制备了多孔高熵 MgAl ₂ O ₄ (HE-MgAl ₂ O ₄ )（最多十元金属：Mg、Ti、V、Cr、Mn、Fe、Co、Ni、Cu 和 Zn）（S _BET  = 139 m ² /g)。对合成化学、不同金属的耐受规律以及结晶的热力学规律进行了很好的研究。二元、三元、四元、五元和二元-MgAl ₂ O _{4 的比较}强调了熵的关键作用，它迫使具有内在不同半径的阳离子占据尖晶石的相似位置。有趣的是，即使在高温湿气 (350°C) 下运行 24 小时，高熵自然赋予 HE-MgAl ₂ O ₄催化剂卓越的稳定性。然后，从头分子动力学研究证明，HE-MgAl ₂ O ₄的热稳定性源于熵稳定效应和动力学稳定结构。此外，在原料气中用 10 vol% 的蒸汽进行CH ₄氧化，HE-MgAl ₂ O ₄保持了原始活性 催化剂持续运行（600°C，100 小时）。