Quinoline is a heterocyclic scaffold of paramount importance to human race. The utility of quinoline derivatives in the areas of medicine, food, catalyst, dye, materials, refineries and electronics is well established. As a result, the synthesis of quinoline core and its derivatives have been an attractive goal for the synthetic organic chemist. In the recent past there have been several new developments in the chemistry associated with quinolines. In pursuit to develop easy and practical approaches to a variety of quinoline derivatives decorated with useful pharmacophores different research workers have made use of new catalysts, medium or physical conditions in several well established synthetic methodologies. Besides an array of new and innovative strategies from novel substrates have been developed which has rendered the synthesis of quinoline core a much simpler process as compared earlier. An assimilation of the literature related to the advances in the syntheses of quinolines and quinoline-annulated ring systems since 2005 is being presented here.

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喹啉和喹啉环系的合成进展

喹啉是一种对人类至关重要的杂环支架。喹啉衍生物在医药、食品、催化剂、染料、材料、炼油厂和电子领域的应用已得到广泛认可。因此，喹啉核及其衍生物的合成一直是合成有机化学家的一个有吸引力的目标。在最近的过去，与喹啉相关的化学有了一些新的发展。为了开发各种用有用药效团修饰的喹啉衍生物的简单实用的方法，不同的研究人员在几种成熟的合成方法中使用了新的催化剂、介质或物理条件。此外，已经开发了一系列来自新型底物的新的和创新的策略，这使得喹啉核心的合成与早期相比变得更加简单。此处介绍了自 2005 年以来与喹啉和喹啉环系统合成进展相关的文献的同化。