The mole fraction solubility data of l-phenylalanine benzyl ester hydrochloride in 11 neat solvents including, methanol, ethanol, n-propanol, n-butanol, n-pentanol, i-butanol, i-propanol, water, acetone, acetonitrile, and ethyl acetate, as well as one binary mixed solvent of methanol + acetone were measured using the static gravimetric method at a temperature interval of “T = 283.15–323.15 K” and a pressure of “p = 98.8 kPa”. The powder X-ray diffraction test was employed to identify the solid-phase characterization of l-phenylalanine benzyl ester hydrochloride in the investigated solvent systems. At constant solvent composition, the solubility was positively correlated with temperature. In the selected monosolvents, the solubility of l-phenylalanine benzyl ester hydrochloride was restricted by multiple factors, and the following order was obtained: methanol > ethanol > n-propanol > n-butanol > n-pentanol > i-butanol > i-propanol > acetone > acetonitrile > ethyl acetate (except for water, which intersects with other solvents). In addition, the modified Apelblat model and the Apelblat–Jouyban–Acree model were employed to fit the solubility data.

中文翻译：

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L-苯丙氨酸苄酯盐酸盐在 283.15 至 323.15 K 范围内在 11 种单独溶剂和甲醇 + 丙酮二元溶剂系统中溶解度的测量和相关性

的摩尔分数溶解度数据升在11种整齐溶剂-苯丙氨酸苄酯盐酸盐，包括甲醇，乙醇，Ñ丙醇，Ñ丁醇，Ñ戊醇，我丁醇，我丙醇，水，丙酮，乙腈，和乙基在“ T = 283.15–323.15 K”的温度区间和“ p = 98.8 kPa”的压力下，使用静态重量法测量乙酸盐以及甲醇+丙酮的一种二元混合溶剂。粉末X射线衍射测试用于鉴定l的固相表征-苯丙氨酸苄酯盐酸盐在所研究的溶剂系统中。在恒定的溶剂组成下，溶解度与温度呈正相关。在所选择的monosolvents，的溶解度升-苯丙氨酸苄基酯盐酸盐由多种因素的限制，并获得下列顺序：甲醇>乙醇> Ñ丙醇> Ñ丁醇> Ñ戊>我丁醇>我丙醇> 丙酮 > 乙腈 > 乙酸乙酯（水除外，它会与其他溶剂相交）。此外，采用修正的 Apelblat 模型和 Apelblat-Jouyban-Acree 模型来拟合溶解度数据。