Synthesis and antiviral activity of sulfonohydrazide and 1,3,4-oxadiazole derivatives of 6,6-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[5,1-b] quinazoline,Journal of Chemical Research

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Synthesis and antiviral activity of sulfonohydrazide and 1,3,4-oxadiazole derivatives of 6,6-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[5,1-b] quinazoline
Journal of Chemical Research ( IF 1.0 ) Pub Date : 2017-04-01 , DOI: 10.3184/174751917x14894997017694
Balaraman Selvakumar _{1,

2} , Saraswathy P. Vaidyanathan ₃ , Subbiah Madhuri ₃ , Kuppanagounder P. Elango ₂

Affiliation

A series of new 6,6-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[5,1-b]quinazoline substituted benzenesulfonohydrazide and 1,3,4-oxadiazole derivatives has been synthesised and characterised using spectral techniques. The antiviral activity of these compounds against an avian paramyxovirus (APMV-1) has been screened and the results show that some of the compounds possess good antiviral activity

中文翻译：

磺酰肼和6,6-二甲基-9-氧代-4,5,6,7,8,9-六氢吡唑并[5,1-b]喹唑啉的1,3,4-恶二唑衍生物的合成和抗病毒活性

合成了一系列新的6,6-二甲基-9-氧代-4,5,6,7,8,9-六氢吡唑并[5,1-b]喹唑啉取代苯磺酰肼和1,3,4-恶二唑衍生物，并使用光谱技术表征。这些化合物对禽副粘病毒（APMV-1）的抗病毒活性已经过筛选，结果表明部分化合物具有良好的抗病毒活性

更新日期：2017-04-01

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