The synthesis of 4-benzoyloxy-5,5-difluoropentan-1-ol from ethyl difluoroacetate is described; its condensation with pyrimidine bases gave carbaacyclonucleosides. which were evaluated, and found inactive, in a large variety of antiviral assays.

中文翻译：

---

二氟化碳环核苷：抗病毒活性的合成和评价

描述了从二氟乙酸乙酯合成 4-苯甲酰氧基-5,5-二氟戊-1-醇；它与嘧啶碱缩合得到碳环核苷。在各种抗病毒试验中对其进行了评估并发现它们没有活性。