A series of novel substituted 8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridines are synthesised from 2,3-dichloro-5-(trifluoromethyl)pyridine, hydrazine hydrate as starting materials by multi-step reactions under microwave irradiation. Their chemical structures can be characterised by 1H NMR, MS and elemental analysis. The title compounds exhibit weak antifungal activity.

中文翻译：

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使用微波辐射轻松一锅合成含有三氟甲基部分的新型 1,2,4-三唑并[4,3- a ]吡啶衍生物

以2,3-二氯-5-(三氟甲基)吡啶、水合肼为原料合成了一系列新型取代的8-氯-6-(三氟甲基)-[1,2,4]三唑并[4,3-a]吡啶类化合物在微波辐射下通过多步反应制备起始材料。它们的化学结构可以通过1H NMR、MS和元素分析来表征。标题化合物表现出弱的抗真菌活性。