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Synthesis of spiro[benzo[4,5]imidazo[2,1-b][1,3]thiazole-2,3-thiolane]s via sulfa-Michael/aldol cascade reactions
Journal of Chemical Research ( IF 1.0 ) Pub Date : 2019-01-01 , DOI: 10.1177/1747519819831898 Jiaying Lei 1 , Xinliang Fu 1 , Yulin Huang 1 , Xiaofang Li 1
Journal of Chemical Research ( IF 1.0 ) Pub Date : 2019-01-01 , DOI: 10.1177/1747519819831898 Jiaying Lei 1 , Xinliang Fu 1 , Yulin Huang 1 , Xiaofang Li 1
Affiliation
The sulfa-Michael/aldol cascade reaction of (Z)-2-arylmethylidene-benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-ones and 1,4-dithiane-2,5-diol afforded novel 2-aryl-4-hydroxy-spiro[benzo[4,5]imidazo[2,1-b][1,3]thiazole-2,3-thiolan]-3-ones in moderate yields. The structures of all the products were characterized thoroughly by nuclear magnetic resonance, infrared and high-resolution mass spectrometry together with X-ray crystallographic analysis.
中文翻译:
通过磺胺-迈克尔/醛醇级联反应合成螺[苯并[4,5]咪唑并[2,1-b][1,3]噻唑-2,3-硫烷]
(Z)-2-芳基亚甲基-苯并[4,5]咪唑并[2,1-b]噻唑-3(2H)-酮和1,4-二噻烷-2,5-的磺胺-迈克尔/醛醇级联反应二醇以中等产率提供新型 2-芳基-4-羟基-螺[苯并[4,5]咪唑并[2,1-b][1,3]噻唑-2,3-硫戊环]-3-酮。所有产物的结构均通过核磁共振、红外和高分辨质谱以及X射线晶体学分析进行了彻底表征。
更新日期:2019-01-01
中文翻译:
通过磺胺-迈克尔/醛醇级联反应合成螺[苯并[4,5]咪唑并[2,1-b][1,3]噻唑-2,3-硫烷]
(Z)-2-芳基亚甲基-苯并[4,5]咪唑并[2,1-b]噻唑-3(2H)-酮和1,4-二噻烷-2,5-的磺胺-迈克尔/醛醇级联反应二醇以中等产率提供新型 2-芳基-4-羟基-螺[苯并[4,5]咪唑并[2,1-b][1,3]噻唑-2,3-硫戊环]-3-酮。所有产物的结构均通过核磁共振、红外和高分辨质谱以及X射线晶体学分析进行了彻底表征。