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Lobelia chinensis: chemical constituents and anticancer activity perspective
Chinese Journal of Natural Medicines ( IF 4.0 ) Pub Date : 2014-02-01 , DOI: 10.1016/s1875-5364(14)60016-9
Mei-Wan CHEN , Wen-Rong CHEN , Jin-Ming ZHANG , Xiao-Ying LONG , Yi-Tao WANG

Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lobelanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applications have also indicated that L. chinensis possesses a number of pharmacological activities (e.g., diuretic, choleretic, breathing excitement, anti-venom, anti-bacterial, and anticancer). This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development of L. chinensis.

中文翻译:

半边莲:化学成分及抗癌活性透视

研究表明,从半边莲中提取了许多以哌啶类生物碱和黄酮类化合物为主的化学成分,如罗贝宁、山茶碱、山茶碱等。实验研究和临床应用还表明,金缕梅具有多种药理活性(如利尿、利胆、呼吸兴奋、抗毒、抗菌和抗癌)。本文重点研究了金缕梅的性质、化学成分和抗癌活性,阐明了它们之间的联系,并鉴定了具有抗癌活性的化合物。这项工作为进一步研究和开发中华白菜奠定了基础。
更新日期:2014-02-01
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