Abstract Synthesis of N-(5-methylisoxazol-3-yl)-2-(5-aryl-1,3,4-oxadiazol-2-yl)acetamides 5a–k was achieved from readily available materials. The compounds were screened for their in vitro antimicrobial activity against representative bacterial and fungal strains. Compounds 5b, 5d and 5f exhibit good activity.

中文翻译：

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异恶唑取代的 1,3,4-恶二唑的合成及抗菌评价

摘要 N-(5-甲基异恶唑-3-基)-2-(5-芳基-1,3,4-恶二唑-2-基)乙酰胺5a-k 的合成是从现成的材料中实现的。筛选化合物对代表性细菌和真菌菌株的体外抗微生物活性。化合物5b、5d和5f表现出良好的活性。