Abstract Baishouwubenzophenone ( 1 ), possessing a unique atropisomeric feature, has been isolated from the roots of Cynanchum wilfordii . The congested structure makes it showing optical activity and consequently the absolute configuration was identified by experimental CD and computational approaches. Configurational assignment was further confirmed by exciton chirality method. The structural features in baishouwubenzophenone molecule allow it to be a potential atropisomeric ligand in asymmetric synthesis.

中文翻译：

---

白首乌二苯甲酮的立体化学，来自 C. wilfordii 的一种独特的阻转异构体

摘要 白首乌二苯甲酮 ( 1 ) 具有独特的阻转异构特征，是从牛心草根中分离得到的。拥挤的结构使其显示出光学活性，因此通过实验 CD 和计算方法确定了绝对构型。通过激子手性方法进一步确认了构型分配。白首乌二苯甲酮分子的结构特征使其成为不对称合成中潜在的阻转异构配体。