PROPOXATE is the proposed generic name for dl-1-(1-phenyl-ethyl)-5-(propoxy-carbonyl)-imidazole HCl. It is a member of a new series of 1-substituted imidazole-5-carboxylic acid esters (Fig. 1). The prototype of this series, Etimidate (proposed generic name for R7405), is an extremely potent, rapid and short-acting hypnotic agent in a variety of animal species1. Propoxate (R7464) is a potent, polyvalent and safe anaesthetic in cold-blooded vertebrates and is very soluble in fresh and salt water. Compared with ‘Tricaine’ (methanesulphonate of meta-amino-benzoic acid ethylester, MS222) it is about 100 times more potent, the active concentration ranging from 0.5 to 10 p.p.m. and from 50 to 1,000 p.p.m. for R7464 and MS222 respectively.

中文翻译：

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丙氧酸盐 (R7464)：一种新的冷血脊椎动物强效麻醉剂

PROPOXATE 是 dl-1-(1-苯基-乙基)-5-(丙氧基-羰基)-咪唑 HCl 的建议通用名称。它是新系列 1-取代咪唑-5-羧酸酯的成员（图 1）。该系列的原型 Etimidate（建议为 R7405 的通用名称）是一种极其有效、快速和短效的催眠剂，可用于多种动物物种 1。丙氧酸盐 (R7464) 是一种强效、多价且安全的冷血脊椎动物麻醉剂，极易溶于淡水和盐水。与“Tricaine”（间氨基苯甲酸乙酯的甲磺酸盐，MS222）相比，它的效力高出约 100 倍，R7464 和 MS222 的活性浓度范围分别为 0.5 至 10 ppm 和 50 至 1,000 ppm。