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2-Bromo-N-(p-toluenesulfonyl)pyrrole: A Robust Derivative of 2-Bromopyrrole
Synlett ( IF 1.7 ) Pub Date : 2003-01-01 , DOI: 10.1055/s-2003-42036
John W. Huffman , Lea W. Knight , Matthew L. Isherwood

2-Bromo-N-(p-toluenesulfonyl)pyrrole (2), a crystalline stable derivative of 2-bromopyrrole (1) has been prepared in 80% yield by bromination of pyrrole, followed by conversion to the N-(p-toluenesulfonyl) derivative. This compound is stable indefinitely at ambient temperature. Compound 2 is an excellent substrate for Suzuki coupling with arylboronic acids.

中文翻译:

2-溴-N-(对甲苯磺酰基)吡咯:2-溴吡咯的稳健衍生物

2-溴-N-(对甲苯磺酰基)吡咯 (2),一种 2-溴吡咯 (1) 的结晶稳定衍生物,通过吡咯溴化,然后转化为 N-(对甲苯磺酰基),收率为 80% ) 衍生物。该化合物在环境温度下无限期地稳定。化合物 2 是 Suzuki 与芳基硼酸偶联的极好底物。
更新日期:2003-01-01
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