Biocompatible Autonomic Self-healing PVA-TA Hydrogel with High Mechanical Strength,Macromolecular Chemistry and Physics

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Biocompatible Autonomic Self-healing PVA-TA Hydrogel with High Mechanical Strength
Macromolecular Chemistry and Physics ( IF 2.5 ) Pub Date : 2021-06-11 , DOI: 10.1002/macp.202100061
Jinxin Huang ₁ , Chengwei Wu ₁ , Xiaogang Yu ₁ , Heng Li ₁ , Shuaiwen Ding ₁ , Wei Zhang ₁

Affiliation

The autonomic self-healing hydrogel with good biocompatibility is generally poor in tensile strength, which seriously hinders its development and application in the field of loaded biomaterials. Here, based on a large number of strong H bonds formed between poly(vinyl alcohol) (PVA) and tannic acid (TA), an autonomic self-healing PVA-TA hydrogel with high strength and high healing efficiency is successfully prepared. The tensile strength of PVA-TA hydrogel is 224 kPa, which can spontaneously restore to 87% of its initial strength within 2 h after fracture without external stimuli. The obtained hydrogel also shows good biocompatibility.

中文翻译：

具有高机械强度的生物相容性自主自愈 PVA-TA 水凝胶

具有良好生物相容性的自主自修复水凝胶的拉伸强度普遍较差，严重阻碍了其在负载生物材料领域的发展和应用。在这里，基于聚乙烯醇（PVA）和鞣酸（TA）之间形成的大量强H键，成功制备了一种具有高强度和高愈合效率的自主自愈PVA-TA水凝胶。PVA-TA水凝胶的拉伸强度为224 kPa，在无外界刺激的情况下，在断裂后2 h内可自发恢复至初始强度的87%。获得的水凝胶还显示出良好的生物相容性。

更新日期：2021-07-08

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