Abstract The unsymmetric precursor ethyl 6‐acetylpyridine‐2‐carboxylate (3) was synthesized from 2,6‐dipiclinic acid (1). On the basis of this precursor, two distinctively different types of compounds were prepared by microwave irradiation under solvent‐free conditions. One type was mono(imino)pyridine compounds (4a–4f), originating from the Schiff base condensation between a series of aromatic amines and the precursor 3; another type was 6‐acetylpyridine‐2‐carboxamide compounds (5a–5c), which were the products of amidation reactions between a series of aliphatic amines and the same precursor 3.

中文翻译：

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6-乙酰吡啶-2-羧酸乙酯与芳香胺/脂肪胺之间的两种新型微波促进反应

摘要 由 2,6-二吡啶甲酸 (1) 合成了不对称前体 6-乙酰吡啶-2-羧酸乙酯 (3)。在这种前体的基础上，在无溶剂条件下通过微波辐射制备了两种截然不同的化合物。一类是单（亚氨基）吡啶化合物（4a-4f），源自一系列芳香胺和前体 3 之间的席夫碱缩合；另一种类型是 6-乙酰吡啶-2-甲酰胺化合物 (5a-5c)，它是一系列脂肪胺与相同前体 3 之间酰胺化反应的产物。