The dynamic coexistence of heterostructures is crucial for the synergistic function of molecularly imprinted polymers (MIPs) derived from high internal phase emulsions (HIPEs). In this work, hydrophilic boronate affinity imprinted hydrogel sorbents (H-UIO-66-NH₂-IHIPEs) were prepared by biphasic synergistic HIPEs droplet reactors filled with reactive microencapsulation system, and used to capture and separate cis-diol containing luteolin (LTL) from complex extraction samples with high selectivity. As the main solid emulsifier, UiO-66-NH₂, prototype zirconium-based metal–organic frameworks (MOFs) greatly improves the mechanical performance of the hydrogel, whilst preventing overuse of surfactants. Space-confined formation of imprinted sites in the external phase is realized in the presence of hydrophilic acrylamide phenylboric acid monomer (H-BA), which endows the specific affinity with pH responsiveness to LTL. In addition, the filled microinclusion compound containing elastic monomer octadecyl methacrylate (SMA) and functional monomer glycidyl methacrylate (GMA) simultaneously added interfacial cross-linking reaction to provide stable pore volume and pore shape. Combined with these excellent properties, H-UIO-66-NH₂-IHIPEs showed fast capture kinetics (75 min) and large uptake amount (39.77 mg g⁻¹) at 298 K, and confirmed the existence of a uniform chemisorption monolayer. Moreover, excellent recyclability of 6.24% loss in adsorption amount after five adsorption–desorption cycles was observed. Finally, the LTL content of the purified product (about 97.38%) was higher than that of the crude extract (about 85.0%). This study sheds a new light for the design of novel imprinted hydrogel sorbents combined with binary synergistic components.

异质结构的动态共存对于源自高内相乳液 (HIPE) 的分子印迹聚合物 (MIP) 的协同作用至关重要。在这项工作中，亲水性硼酸盐亲和印迹水凝胶吸附剂 (H-UIO-66-NH ₂ -IHIPEs) 通过双相协同 HIPEs 液滴反应器制备，该反应器充满反应性微囊系统，用于捕获和分离含有木犀草素 (LTL) 的顺式二醇从具有高选择性的复杂提取样品中提取。作为主要的固体乳化剂，UiO-66-NH ₂，原型锆基金属有机框架（MOF）大大提高了水凝胶的机械性能，同时防止过度使用表面活性剂。在亲水性丙烯酰胺苯基硼酸单体 (H-BA) 的存在下，外相中印迹位点的空间受限形成被实现，这赋予了对 LTL 的 pH 响应性的特定亲和力。此外，含有弹性单体甲基丙烯酸十八烷基酯（SMA）和功能性单体甲基丙烯酸缩水甘油酯（GMA）的填充微包合物同时加入界面交联反应，提供稳定的孔体积和孔形状。结合这些优异的特性，H-UIO-66-NH ₂ -IHIPEs 表现出快速的捕获动力学（75 分钟）和大的吸收量（39.77 mg g ^-1) 在 298 K，并证实存在均匀的化学吸附单层。此外，观察到五个吸附-解吸循环后吸附量损失 6.24% 的优异可回收性。最后，纯化产物的LTL含量（约97.38%）高于粗提物（约85.0%）。该研究为结合二元协同成分的新型印迹水凝胶吸附剂的设计提供了新的思路。