A Physically Cross-Linked Sodium Alginate–Gelatin Hydrogel with High Mechanical Strength,ACS Applied Polymer Materials

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A Physically Cross-Linked Sodium Alginate–Gelatin Hydrogel with High Mechanical Strength
ACS Applied Polymer Materials ( IF 4.4 ) Pub Date : 2021-05-21 , DOI: 10.1021/acsapm.1c00404
Lini Wang ₁ , Hui Jie Zhang ₁ , Xueqian Liu ₁ , Yun Liu ₁ , Xing Zhu ₁ , Xinhua Liu ₁ , Xiangyu You ₁

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Hydrogels constructed from pure biomacromolecules with multifunctions of good mechanical performances, ionic environmental stability, self-healing, biocompatibility, and ionic conductivity are desirable but remain as a challenge. In this work, hydrogels composed of pure biomacromolecules of gelatin and sodium alginate were constructed through a simple repeated acid soaking–drying–swelling process. The obtained hydrogel with a physically cross-linked interpenetrated network of gelatin and sodium alginate contained 79% water and had a relatively high fracture tensile stress and strain of 0.46 MPa and 2.4, respectively. As the gel was cross-linked with a hydrogen bond and alginic acid, it exhibited good stability in a physiological saline solution. Furthermore, the gel exhibited good biocompatibility, self-healing properties, and ionic conductivity, demonstrating its excellent potential for applications in biomedical materials and biosensors.

中文翻译：

一种具有高机械强度的物理交联海藻酸钠-明胶水凝胶

由具有良好机械性能、离子环境稳定性、自修复、生物相容性和离子电导率等多种功能的纯生物大分子构建的水凝胶是理想的，但仍然是一个挑战。在这项工作中，由明胶和海藻酸钠的纯生物大分子组成的水凝胶是通过简单的重复酸浸-干燥-膨胀过程构建的。所获得的具有物理交联的明胶和海藻酸钠互穿网络的水凝胶含有 79% 的水，并具有相对较高的断裂拉伸应力和应变，分别为 0.46 MPa 和 2.4。由于凝胶通过氢键与海藻酸交联，因此在生理盐水溶液中表现出良好的稳定性。此外，凝胶表现出良好的生物相容性、自愈性和离子导电性，

更新日期：2021-06-11

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