A concise and scalable synthesis of a 2,6-diazaspiro[3.3]heptane building block is reported. The usefulness of this structural surrogate of piperazine is shown in arene amination reactions yielding a variety of N-Boc- N'-aryl-2,6-diazaspiro[3.3]heptanes.

中文翻译：

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2,6-二氮杂螺[3.3]庚烷：合成及其在钯催化的芳基胺化反应中的应用。

简明和可扩展的合成2,6-二氮杂螺[3.3]庚烷结构单元。哌嗪的这种结构替代物的有用性在产生各种N-Boc-N'-芳基-2,6-二氮杂螺[3.3]庚烷的芳烃胺化反应中显示。