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Injectable Microfluidic Hydrogel Microspheres for Cell and Drug Delivery
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2021-05-13 , DOI: 10.1002/adfm.202103339
Zhenyu Zhao 1, 2 , Zhen Wang 2 , Gen Li 2 , Zhengwei Cai 2 , Jiezhou Wu 1 , Lei Wang 2 , Lianfu Deng 2 , Ming Cai 1 , Wenguo Cui 2
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2021-05-13 , DOI: 10.1002/adfm.202103339
Zhenyu Zhao 1, 2 , Zhen Wang 2 , Gen Li 2 , Zhengwei Cai 2 , Jiezhou Wu 1 , Lei Wang 2 , Lianfu Deng 2 , Ming Cai 1 , Wenguo Cui 2
Affiliation
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Microfluidic hydrogel microspheres have been broadly studied across a wide range of industries and applications, and their use in the medical field, including control cells and drug delivery, is increasing. The usual design of these materials is intended to enable the efficient and smart encapsulation of cells and/or drugs in microspheres in which the functionalities and features are effectively controlled, lending itself some unique properties. These characteristics promote exchanges and cooperation in multiple disciplines and boost the development of precision medicine, new manufacturing technologies, and applied materials. This review begins with a discussion of microfluidic hydrogel microspheres and then introduces the preparation equipment, main principles, and related characteristics of the microspheres. Furthermore, the medical applications of microfluidic hydrogel microspheres for delivering cells and drugs are emphasized. Finally, this review discusses perspectives and future directions for accelerating the development and application of microfluidic hydrogel microspheres for controlled delivery.
中文翻译:
用于细胞和药物递送的可注射微流体水凝胶微球
微流体水凝胶微球已在广泛的行业和应用中得到广泛研究,并且它们在医学领域(包括控制细胞和药物递送)中的应用正在增加。这些材料的通常设计旨在将细胞和/或药物有效和智能地封装在微球中,其中的功能和特征得到有效控制,从而赋予自身一些独特的特性。这些特点促进了多学科的交流与合作,推动了精准医学、新型制造技术和应用材料的发展。本综述首先讨论了微流体水凝胶微球,然后介绍了微球的制备设备、主要原理和相关特性。此外,强调了微流体水凝胶微球在递送细胞和药物方面的医学应用。最后,这篇综述讨论了加速微流控水凝胶微球控制递送的开发和应用的前景和未来方向。
更新日期:2021-05-13
中文翻译:

用于细胞和药物递送的可注射微流体水凝胶微球
微流体水凝胶微球已在广泛的行业和应用中得到广泛研究,并且它们在医学领域(包括控制细胞和药物递送)中的应用正在增加。这些材料的通常设计旨在将细胞和/或药物有效和智能地封装在微球中,其中的功能和特征得到有效控制,从而赋予自身一些独特的特性。这些特点促进了多学科的交流与合作,推动了精准医学、新型制造技术和应用材料的发展。本综述首先讨论了微流体水凝胶微球,然后介绍了微球的制备设备、主要原理和相关特性。此外,强调了微流体水凝胶微球在递送细胞和药物方面的医学应用。最后,这篇综述讨论了加速微流控水凝胶微球控制递送的开发和应用的前景和未来方向。