ABSTRACT

The mites Demodex folliculorum (Simon) and Demodex brevis Akbulatova are part of the regular human skin fauna, found in the pilosebaceous unit, and their infestations might cause the disease known as demodicosis. Inflammatory response is triggered by this interaction in patients, causing the appearance of several facial dermatoses. In the present revision, mites will be characterized and their association with dermatological diseases shall be discussed, as well as diagnostic methods, immune response to their infestations, and the major treatments used for Demodex-related cases. Demodex infestations both in hair follicles (D. folliculorum) and in sebaceous glands (D. brevis) might lead to the aggravation of dermato-facial pathologies, and trigger a local inflammatory reaction in many cases, associated with mite density and their potential as vectors of pathogenic microorganisms. The treatments for these Demodex-associated pathologies have proven to be effective, particularly in decreasing density, and consequently, in mitigating symptoms and the overall patient clinical condition.

摘要

螨虫毛囊蠕形螨（西门）和皮脂蠕形螨Akbulatova是正规的人体皮肤的动物，在毛囊皮脂腺单位发现的一部分，它们的侵袭可能导致被称为demodicosis疾病。炎症反应是由患者的这种相互作用触发的，导致出现几种面部皮肤病。在本次修订中，将对螨虫进行表征并讨论它们与皮肤病的关系，以及诊断方法、对其侵染的免疫反应以及用于蠕形螨相关病例的主要治疗方法。毛囊（D. folliculorum）和皮脂腺（D. brevis）中的蠕形螨感染) 可能会导致皮肤面部病变的加重，并在许多情况下引发局部炎症反应，这与螨密度及其作为病原微生物载体的潜力有关。这些蠕形螨相关病理的治疗已被证明是有效的，特别是在降低密度方面，并因此在减轻症状和整体患者临床状况方面。