Imidazo[1,2-a]pyridines are a class of valuable heterocyclic scaffolds in organic synthesis and pharmaceutical chemistry. The direct functionalization of this valuable scaffold has been considered as one of the most efficient strategies for the construction of imidazo[1,2-a]pyridine derivatives. This review summarizes the recent advances in radical reactions for the direct functionalization of imidazo[1,2-a]pyridines through transition metal catalysis, metal-free oxidation, and photocatalysis strategies.

中文翻译：

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咪唑并[1,2-a]吡啶经自由基反应官能化

咪唑并[1,2- a ]吡啶是有机合成和药物化学中的一类有价值的杂环骨架。这种有价值的支架的直接功能化已被认为是构建咪唑并[1,2- a ]吡啶衍生物的最有效策略之一。这篇综述总结了通过过渡金属催化，无金属氧化和光催化策略将咪唑并[1,2- a ]吡啶直接官能化的自由基反应的最新进展。