动脉瘤栓塞手术模拟分析：不同栓塞率（CTA）的动脉瘤血液流变学,Bio-Medical Materials and Engineering

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动脉瘤栓塞手术模拟分析：不同栓塞率（CTA）的动脉瘤血液流变学
Bio-Medical Materials and Engineering ( IF 1.0 ) Pub Date : 2021-05-11 , DOI: 10.3233/bme-211225
Quan Bao ₁ , Xin Meng ₂ , Mingcheng Hu ₁ , Jian Xing ₁ , Dan Jin ₃ , He Liu ₁ , Jie Jiang ₄ , Yanwei Yin ₁

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背景：栓塞程度是影响动脉瘤复发的重要因素。目的：分析不同栓塞程度的血流动力学参数在动脉瘤发生、发展及后治疗中的作用，确定血流动力学治疗后引起动脉瘤发生和复发的具体因素。本研究为动脉瘤的防治提供了理论依据。方法：使用脑动脉瘤患者的计算机断层扫描血管造影 (CTA) 数据分别对 0%、24%、52%、84% 和 100% 的血管内栓塞进行建模。时间平均壁面剪应力、时间平均壁面剪应力、振荡剪切指数、采用血流动力学形成指标和相对保留时间分析不同栓塞模型血流动力学指标的变化。结果：随着栓塞率的增加，时间平均壁剪应力、时间平均壁剪应力等级和动脉瘤指数形成逐渐增加，相对保留时间逐渐减小。振荡剪切指数在不完全栓塞的患者中较高，在完全栓塞的患者中降低。结论：随着栓塞程度的增加，血流趋于稳定，降低了脑动脉瘤破裂的风险，发现血管连接壁容易受到损伤。时间平均壁剪应力等级和动脉瘤指数形成逐渐增加，相对保留时间值逐渐减小。振荡剪切指数在不完全栓塞的患者中较高，在完全栓塞的患者中降低。结论：随着栓塞程度的增加，血流趋于稳定，降低了脑动脉瘤破裂的风险，发现血管连接壁容易受到损伤。时间平均壁剪应力等级和动脉瘤指数形成逐渐增加，相对保留时间值逐渐减小。振荡剪切指数在不完全栓塞的患者中较高，在完全栓塞的患者中降低。结论：随着栓塞程度的增加，血流趋于稳定，降低了脑动脉瘤破裂的风险，发现血管连接壁容易受到损伤。

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Simulation analysis of aneurysm embolization surgery: Hemorheology of aneurysms with different embolization rates (CTA)

BACKGROUND:Embolization degree acts as an important factor affecting recurrence of aneurysm. OBJECTIVE:To analyze the role of hemodynamics parameters of different degrees of embolization in the occurrence, development and post-treatment of aneurysms, and to determine the specific factors causing the occurrence and recurrence of aneurysms after hemodynamics treatment. Our study provides a theoretical basis for the prevention and treatment of aneurysms. METHODS:Computed Tomography Angiography (CTA) data of a patient with cerebral aneurysm were used to model 0%, 24%, 52%, 84% and 100% of endovascular embolization, respectively. The time average wall shear stress, time average wall shear stress, oscillatory shear index, hemodynamics formation index and relative retentive time were used to analyze the changes of hemodynamics indexes in different embolic models. RESULTS:With the increase of embolic rate, the values of time average wall shear stress, time average wall shear stress grade and aneurysm index formation gradually increased, and the values of relative retention time gradually decreased. Oscillatory shear index was higher in patients with incomplete embolization and decreased in patients with complete embolization. CONCLUSIONS:As the degree of embolization increased, the blood flow tended to stabilize, reducing the risk of cerebral aneurysm rupture, and finding that the wall of the vessel junction was susceptible to injury.

更新日期：2021-05-11

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