Novel Microfluidic Device for the Preparation of Multiple Microproducts,Industrial & Engineering Chemistry Research

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Novel Microfluidic Device for the Preparation of Multiple Microproducts
Industrial & Engineering Chemistry Research ( IF 3.8 ) Pub Date : 2021-05-11 , DOI: 10.1021/acs.iecr.1c01094
Yu Han ₁ , Xiaofei Xu ₁ , Fengxia Liu ₁ , Wei Wei ₁ , Zhijun Liu ₁

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Double-layered microbubbles, microdroplets, and a mixture of microproducts were fabricated by a novel device of the geometric combination of a Y-junction and a flow-focusing junction in this study. An air-in-oil-in-water microbubble was used as a template for the preparation of double-layered microbubbles. The oil-in-water microdroplets and multiple microproducts could be generated in this system at the same time. To observe the evolution of the multiphase flow in a microchannel, high-speed microscopy and digital imaging technologies were applied. The fluidic mechanisms of generating specific microproducts under different operating conditions were investigated through the analysis of the flow patterns. The analysis of the microproduct generation process showed that operating conditions such as the air pressure and oil- and aqueous-phase flow rates had a significant impact on the size, generation frequency, and monodispersity of the microproducts. Dimensional analysis was applied to predict the diameters of the microproducts and showed a good agreement. Finally, the method to promote the emulsion stability was obtained.

中文翻译：

用于制备多种微产品的新型微流控装置

在这项研究中，通过Y结和流聚焦结的几何组合的新型装置制造了双层微泡，微滴和微产品的混合物。将水包油中的空气微泡用作制备双层微泡的模板。在该系统中可以同时产生水包油微滴和多种微产品。为了观察微通道中多相流的演变，应用了高速显微镜和数字成像技术。通过对流型的分析，研究了在不同操作条件下产生特定微产品的流体机理。对微产品生成过程的分析表明，操作条件（例如气压，油相和水相流速）对微产品的尺寸，生成频率和单分散性有重大影响。进行了尺寸分析以预测微产品的直径，并显示出良好的一致性。最后，获得了促进乳液稳定性的方法。

更新日期：2021-05-19

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