Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Neuropediatrics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Rheumatology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Three consecutive skeletal muscle biopsies during a several months time-frame, showing different degrees of neutral lipid storage. This is highlighted by Oil-red-O stains (D, E, F) and electron microscopy (G, H, I). Note the impact on mitochondrial morphology with so called 'parking lots (K, L). Zooming 'in and out' into the ultrastructure, using the nanotomy platform provides interesting detailled information (http://nanotomy.org).
中文翻译：
血浆置换和免疫球蛋白治疗严重脂质贮积性肌病的成功：以错误的理由做正确的事
在几个月的时间范围内连续进行了三次骨骼肌活检，显示出不同程度的中性脂质储存。油红 O 染色剂（D、E、F）和电子显微镜（G、H、I）突出显示了这一点。注意所谓的“停车场（K，L）对线粒体形态的影响。使用 nanotomy 平台“放大和缩小”超微结构可提供有趣的详细信息 (http://nanotomy.org)。
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