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Six 19,20-epoxycytochalasans from endophytic Diaporthe sp. RJ-47
Natural Product Research ( IF 1.9 ) Pub Date : 2020-12-16 , DOI: 10.1080/14786419.2020.1859504
Qiong Zhang 1 , Zhi-Pu Huang 1 , Yu-Ying Zhao 1 , Qing Zhao 1 , Jian-Hong Chen 2 , Wei-Guang Ma 1 , Xiao-Mei Zhang 1
Affiliation  

Abstract

Two new cytochalasins, deacetyl-19-epi-cytochalasin P1 (1), deacetyl-19,20-epoxycytochalasin D (2) were isolated from the endophytic fungus Diaporthe sp. RJ-47, along with four known compounds deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C (3), 19,20-epoxycytochalasin Q (4), 19,20-epoxycytochalasin C (5) and deacetyl-19,20-epoxy cytochalasin C (6). Their structures were unambiguously elucidated on the basis of the comprehensive analysis of extensive spectroscopic data. The antimicrobial effects of these compounds were evaluated.



中文翻译:

来自内生 Diaporthe sp. 的六个 19,20-环氧细胞松弛素。RJ-47

摘要

从内生真菌Diaporthe sp.中分离出两种新的细胞松弛素 deacetyl-19- epi- cytochalasin P1 ( 1 )、deacetyl-19,20-epoxycytochalasin D ( 2 ) 。RJ-47,以及四种已知化合物 deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C ( 3 )、19,20-epoxycytochalasin Q ( 4 )、19,20-epoxycytochalasin C ( 5 )和 deacetyl-19,20-epoxy cytochalasin C ( 6 )。在对广泛的光谱数据进行综合分析的基础上,明确阐明了它们的结构。评估了这些化合物的抗微生物作用。

更新日期:2020-12-16
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