Abstract Background: Both acupoint injection and sacral canal injection are widely adopted in the treatment of lumbar disc herniation (LDH), but there are still doubts about the effectiveness and safety of the 2 methods. Therefore, the objective of the randomized controlled trial is to evaluate the effectiveness and safety of acupoint injection and sacral canal injection in the treatment of LDH. Method: This is a prospective randomized controlled trial to study the effectiveness and safety of acupoint injection and sacral canal injection in the treatment of LDH. With the approval by the clinical research ethics committee of our hospital, patients were randomly included into 1 of 2 treatment protocols:(1) acupoint injection group and(2) sacral canal injection group. Patients, doctors, nurses, and research assistants responsible for collecting data were blinded to group allocation. Main outcome observation indicator: visual analogue scale; secondary outcome observation indicator: Oswestry disability index scores; paresthesia score; adverse reactions. Data were analyzed using the statistical software package SPSS version 25.0 (Chicago, IL). Discussion: The effectiveness and safety of acupoint injection and sacral canal injection in the treatment of LDH were evaluated in this study, and the results of this trial would establish clinical evidence for the adoption of acupoint injection or sacral canal injection to treat LDH. Trial registration number: DOI 10.17605 / OSF.IO / VTFUD

中文翻译：

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穴位注射与骶管注射治疗腰椎间盘突出症的比较


摘要背景：穴位注射和骶管注射均广泛应用于治疗腰椎间盘突出症（LDH），但两种方法的有效性和安全性仍存在疑问。因此，随机对照试验的目的是评价穴位注射和骶管注射治疗LDH的有效性和安全性。方法：这是一项前瞻性随机对照试验，研究穴位注射和骶管注射治疗LDH的有效性和安全性。经我院临床研究伦理委员会批准，患者被随机分为2个治疗方案中的1个：（1）穴位注射组和（2）骶管注射组。负责收集数据的患者、医生、护士和研究助理对分组分配不知情。主要结局观察指标：视觉模拟量表；次要结局观察指标：Oswestry残疾指数评分；感觉异常评分；不良反应。使用统计软件包 SPSS 25.0 版（芝加哥，伊利诺伊州）分析数据。讨论：本研究评价穴位注射和骶管注射治疗LDH的有效性和安全性，本试验结果为采用穴位注射或骶管注射治疗LDH提供临床证据。试用注册号：DOI 10.17605 / OSF.IO / VTFUD