Background: Nanosuspensions are colloidal systems consisting of pure drug and stabilizers, without matrix or lyophilized into a solid matrix. Nanosuspensions improve the solubility of the drug both in the aqueous and organic phases. Nanosuspensions are also known as brick dust molecules, as they increase the dissolution of a system and improve absorption.

Methods: Extensive information related to nanosuspensions and its associated patents were collected using Pub Med and Google Scholar.

Results: Over the last decade nanosuspensions have attracted tremendous interest in pharmaceutical research. It provides unique features including, improved solubility, high drug loading capacity, and passive targeting. These particles are cost-effective, simple, and have lesser side effects with minimal dose requirements. However, the stability of nanosuspensions still warrants attention.

Conclusion: Nanosuspensions play a vital role in handling the numerous drug entities with difficult physico-chemical characteristics such as solubility and can further aid with a range of routes that include nasal, transdermal, ocular, parenteral, pulmonary etc. This review highlights the relevance of nanosuspensions in achieving safe, effective and targeted drug delivery.

背景：纳米混悬剂是由纯药物和稳定剂组成的胶体系统，没有基质或冻干成固体基质。纳米混悬剂提高了药物在水相和有机相中的溶解度。纳米悬浮液也被称为砖粉分子，因为它们可以增加系统的溶解并改善吸收。

方法：使用 Pub Med 和 Google Scholar 收集了与纳米混悬剂及其相关专利相关的大量信息。

结果：在过去十年中，纳米混悬剂引起了药物研究的极大兴趣。它提供了独特的功能，包括改善的溶解度、高载药量和被动靶向。这些颗粒具有成本效益、简单、副作用较小、剂量要求低的特点。然而，纳米混悬剂的稳定性仍然值得关注。

结论：纳米混悬剂在处理具有困难的物理化学特征（例如溶解度）的众多药物实体方面发挥着至关重要的作用，并且可以进一步帮助一系列途径，包括鼻腔、透皮、眼部、肠胃外、肺部等。本综述强调了纳米混悬液实现安全、有效和靶向给药。