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Central, but not peripheral, nervous system ERK2 is essential for itch signals in murine allergic skin inflammation
Allergy ( IF 12.6 ) Pub Date : 2021-04-21 , DOI: 10.1111/all.14867 Shinsuke Matsuo 1 , Takashi Hashimoto 1 , Fumhiro Matsuura 2 , Osamu Imamura 3 , Shogo Endo 4 , Yasushi Satoh 3 , Takahiro Satoh 1
Allergy ( IF 12.6 ) Pub Date : 2021-04-21 , DOI: 10.1111/all.14867 Shinsuke Matsuo 1 , Takashi Hashimoto 1 , Fumhiro Matsuura 2 , Osamu Imamura 3 , Shogo Endo 4 , Yasushi Satoh 3 , Takahiro Satoh 1
Affiliation
Itch is a common cutaneous symptom in a variety of dermatological diseases, but detailed neuropathological mechanisms remain to be fully elucidated. This study aimed to assess in vivo ERK2 functions in the nervous system for itch responses.
中文翻译:
中枢而非外周神经系统 ERK2 对小鼠过敏性皮肤炎症中的瘙痒信号至关重要
瘙痒是多种皮肤病常见的皮肤症状,但详细的神经病理机制仍有待充分阐明。本研究旨在评估体内ERK2 在神经系统中对瘙痒反应的功能。
更新日期:2021-04-21
中文翻译:
中枢而非外周神经系统 ERK2 对小鼠过敏性皮肤炎症中的瘙痒信号至关重要
瘙痒是多种皮肤病常见的皮肤症状,但详细的神经病理机制仍有待充分阐明。本研究旨在评估体内ERK2 在神经系统中对瘙痒反应的功能。