当前位置: X-MOL 学术Phytochem. Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Isolation and characterization of triterpenoid saponins from leaves of Aralia nudicaulis L
Phytochemistry Letters ( IF 1.3 ) Pub Date : 2021-04-21 , DOI: 10.1016/j.phytol.2021.04.004
Serge Lavoie , Julie Pierra , Jean Legault , Diamondra Raminoson , Quentin Lion , Vakhtang Mshvildadze , André Pichette

Three new oleanolic glycosides (13), along with seven known saponins from various plants (410) were isolated for the first time from the leaves of Aralia nudicaulis. Their structures were elucidated on the basis of spectroscopic evidence, including 1D and 2D NMR, and HRESIMS. Nudicauloside A and B (12) have shown moderate anti-inflammatory activity, as demonstrated by inhibition of LPS-induced NO production in raw 264.7 murine macrophages (IC50 = 74–101 μM).



中文翻译:

分离和三萜皂苷的特征从叶龙牙nudicaulis大号

三个新的齐墩果甙(1 - 3)中,用从各种植物7个已知皂苷沿(4 - 10)中分离首次从叶龙牙nudicaulis。根据包括1D和2D NMR以及HRESIMS在内的光谱学证据阐明了它们的结构。Nudicauloside A和B(1 - 2)已显示适中的抗炎活性,通过在原始264.7小鼠巨噬细胞LPS诱导的NO产生的抑制所证实(IC 50  = 74-101μM)。

更新日期:2021-04-21
down
wechat
bug